Control of nanoparticle cellular uptake and therapeutic efficacy through YAP signaling

NenoVision

Explore how YAP signaling influences cellular uptake and response to nanoparticles. This research reveals promising findings using AFM-in-SEM LiteScope to control YAP, enhancing nanoparticle therapy efficacy, particularly for triple-negative breast cancer.

Fascinating work by Marco Cassani and team on the role of YAP signaling in nanoparticle internalization for better cancer therapy!

We are proud that LiteScope AFM-in-SEM was part of their study, supporting the detailed analysis of cell mechanics and nanoparticle interactions. Their research provides groundbreaking insights into the molecular processes of how YAP (Yes-associated protein) a key component in the Hippo signaling pathway regulates the internalization of nanoparticles in triple-negative breast cancer (TNBC) cells.

We’re excited to see how this work advances the field of nanomedicine and cancer therapy, and proud to have played a part in their success with LiteScope AFM-in-SEM.

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